Mitogen-Activated Protein Kinases Mediate Matrix Metalloproteinase-9 Expression in Vascular Smooth Muscle Cells
- 1 December 2000
- journal article
- research article
- Published by Wolters Kluwer Health in Arteriosclerosis, Thrombosis, and Vascular Biology
- Vol. 20 (12) , 2527-2532
- https://doi.org/10.1161/01.atv.20.12.2527
Abstract
—Expression of matrix metalloproteinase (MMP)-9 has been linked to the progression of plaque rupture and intimal formation in arterial lesions. In this study, we determined which factors an...Keywords
This publication has 22 references indexed in Scilit:
- p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-κB activity and Fas expressionOncogene, 2000
- SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1Published by Wiley ,2000
- Synergistic upregulation of metalloproteinase‐9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF‐κBFEBS Letters, 1998
- Activation of the Protein Kinase p38 in the Spindle Assembly Checkpoint and Mitotic ArrestScience, 1998
- The search for physiological substrates of MAP and SAP kinases in mammalian cellsTrends in Cell Biology, 1997
- Mitogen-activated protein kinase pathwaysCurrent Opinion in Cell Biology, 1997
- Regulation of 92 kDa type IV collagenase expression by the jun aminoterminal kinase- and the extracellular signal-regulated kinase-dependent signaling cascadesOncogene, 1997
- Stress-Induced Phosphorylation and Activation of the Transcription Factor CHOP (GADD153) by p38 MAP KinaseScience, 1996
- Secretion of stromelysin by cultured dermal papilla cells: Differential regulation by growth factors and functional role in mitogen‐induced cell proliferationJournal of Cellular Physiology, 1992
- Characteristics of a 95-kDa matrix metalloproteinase produced by mammary carcinoma cellsBiochemistry, 1991