Synthesis of C-Nucleosides Having Typical Aromatic Heterocycles as the Base Moiety
- 1 January 1993
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1993 (05) , 517-520
- https://doi.org/10.1055/s-1993-25896
Abstract
A 2,3,5-tri-O-benzyl-D-ribose reacts with lithium salts of thiophenes or furans to give the corresponding 2-ribosylthiophenes or furans, which are then treated with p-toluenesulfonic acid, affording 2-ribofuranosylthiophenes or furans (C-nucleosides) in good yield and in a stereoselective manner.Keywords
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