Role of the cAMP and MAPK pathways in the transformation of mouse 3T3 fibroblasts by a TSHR gene constitutively activated by point mutation
Open Access
- 5 October 2000
- journal article
- research article
- Published by Springer Nature in Oncogene
- Vol. 19 (42) , 4896-4905
- https://doi.org/10.1038/sj.onc.1203852
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- Protein Kinase A-Dependent and -Independent Signaling Pathways Contribute to Cyclic AMP-Stimulated ProliferationMolecular and Cellular Biology, 1999
- Oncogenic potential of a mutant human thyrotropin receptor expressed in FRTL-5 cellsOncogene, 1998
- G PROTEIN βγ SUBUNITSAnnual Review of Pharmacology and Toxicology, 1997
- Germline mutations in the thyrotropin receptor gene cause non–autoimmune autosomal dominant hyperthyroidismNature Genetics, 1994
- Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cellsCell, 1994
- Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunitsNature, 1994
- G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity.Proceedings of the National Academy of Sciences, 1991
- Signal Transduction by the Human Thyrotropin Receptor: Studies on the Role of Individual Amino Acid Residues in the Carboxyl Terminal Region of the Third Cytoplasmic LoopMolecular Endocrinology, 1991
- Receptor-effector coupling by G proteinsBiochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1990
- A family of receptors coupled to guanine nucleotide regulatory proteinsBiochemistry, 1987