Effect of Frequent Rinses with Isomaltulose (Palatinose®) Solution on Acid Production in Human Dental Plaque

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Abstract
Acid production from glucose and isomaltulose (Palatinose) in dental plaque suspensions was studied before and after subjects rinsed their mouths 6 times daily for 6 wk with a 15% wt/vol isomaltulose solution. The mean acid production from isomaltulose, expressed in percent of that from glucose, increased significantly (P < 0.01) after the rinsing period. In vivo plaque pH changes caused by a mouth rinse with 10 ml of a 15% wt/vol glucose or isomaltulose solution were determined also, before and after the rinsing period. The pH decreases from isomaltulose were significantly more pronounced after the rinsing period (P < 0.01) and the raw pH values were .apprx. 0.57 U lower than before (P < 0.001), but never below pH 6.2. Isomaltulose was considerably less acidogenic than glucose before as well as after the isomaltulose rinsing period (P < 0.001).