Demethylchlortetracycline-Induced Fluorescence of Gastric Sediment
- 31 March 1962
- journal article
- research article
- Published by American Medical Association (AMA)
- Vol. 179 (13) , 997-1000
- https://doi.org/10.1001/jama.1962.03050130001001
Abstract
The demonstration of fluorescent material in gastric sediment after the oral administration of demethylchlortetracycline (Declomycin) may serve to differentiate malignant from benign gastric lesions. In a study of 58 patients with a variety of benign and malignant disorders of the stomach, all 10 patients with cancer and 2 patients with a benign gastric ulcer showing mucosal atypism gave a positive test. Of the 46 patients with normal stomachs or clearly benign disorders, only 1 gave a positive test. The test for induced fluorescence of gastric sediment is simple to perform, but certain technical aspects must be observed to insure an accurate result.Keywords
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