Biosynthesis of lasalocid A. Metabolic interrelationships of carboxylic acid precursors and polyether antibiotics.

Abstract
The metabolic interrelationships of isobutyrate, n-butyrate, and propionate in Streptomyces lasaliensis are established to show how these acids are used as precursors for the biosynthesis of the polymer antibiotic, lasalocid A.