INDUCTION OF SISTER CHROMATID EXCHANGES IN Allium cepa MERISTEMATIC CELLS EXPOSED TO meso‐ TETRA(4‐PYRIDYL) PORPHINE and HEMATOPORPHYRIN PHOTORADIATION

1 October 1987

journal article
research article
Published by Wiley in Photochemistry and Photobiology

Vol. 46 (4) , 463-467
https://doi.org/10.1111/j.1751-1097.1987.tb04796.x

Abstract

The photodynamic effect of two porphyrin derivatives,meso‐tetra(4‐pyridyl)porphine (T₄PyP) and hematoporphyrin (HP), and activating red light (647.1 nm) was tested, measuring the number of sister chromatid exchanges induced by this treatment inAllium cepachromosomes. A significant increase in the frequencies of sister chromatid exchanges was observed when chromosomes substituted with 5‐bromo‐2′‐deoxyuridine were treated for 4 h (G₁of the second cycle of division) with T₄PyP or HP followed by an irradiation with red light for 5 min.

This publication has 26 references indexed in Scilit:

Photodynamic effect of the porphyrin derivative meso-tetra (4-N-methylpyridyl) porphine on sister chromatid exchanges in meristematic cells
Cellular and Molecular Life Sciences, 1986
Chromosomal aberrations and SCEs in Allium cepa root-tip cells treated with caffeine and pyronin Y
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1984
Interactions of porphyrins with nucleic acids
Biochemistry, 1983
Stimulated Human Phagocytes Produce Cytogenetic Changes in Cultured Mammalian Cells
New England Journal of Medicine, 1983
Circular dichroism spectroscopy of a cationic porphyrin bound to DNA
Biochemical and Biophysical Research Communications, 1982
On the involvement of singlet oxygen in mutation induction by 8-methoxypsoralen and UVA irradiation in Escherichia coli K-12
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1981
A replication model for sister-chromatid exchange
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1980
The solution spectroscopy of drugs and the drug-nucleic acid interactions
Progress in Biophysics and Molecular Biology, 1979
SISTER CHROMATID EXCHANGE
Annual Review of Genetics, 1977
Colchicine and Caffeine in the Estimate of Cell Flow and Cycle Time in Allium Roots
CYTOLOGIA, 1971