Multieentre Clinical Trials and Variance Components

1 January 1990

journal article
research article
Published by Wiley in Biometrical Journal

Vol. 32 (5) , 545-550
https://doi.org/10.1002/bimj.4710320505

Abstract

A method of analysing regression data is presented for a model in which the dependent variable has a binomial distribution and the regression contains both fixed and random components. The method is then used to analyse treatment success data for a multicentre clinical trial study.

Keywords

MIXED MODEL
BINOMIAL LOGIT
DISCRETE REGRESSION
MULTICENTRE CLINICAL TRIAL

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