SPHEROID DEGENERATION OF CORNEA AND CONJUNCTIVA

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Abstract
The incidence of spheroid degeneration was studied in a series of 659 Iskimos from Arctic South-West Greenland and 1 of 810 Caucasians in Copenhagen with its temperate climate. The over-all prevalence was highest among the Eskimos (12.3 compared to 4.1% among the people of Copenhagen, P < 0.001). The prevalence was independent of sex, but increased with age (however, with a fall again after the age of 70 yr in Copenhagen). The spheroid deposits were present on the conjunctiva in 74% of the subjects, on the cornea in 18% and at both sites in 8%. Of the subjects, 71% displayed autofluorescent globular deposits. These constituted 10% of the total number of globules. The number of globules per subject averaged 30. Spheroid degeneration was rarely found temporally in Eskimos. Spheroid degenerative processes are most frequently seen in pingueculae, but are not considered to bear any relation to pterygium.

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