Effect of Concanavalin A on the Early Events of Rabies Virus Infection of CER Cells
- 1 January 1985
- journal article
- research article
- Published by S. Karger AG in Intervirology
- Vol. 24 (3) , 166-169
- https://doi.org/10.1159/000149636
Abstract
The effect of concanavalin A on rabies virus infection of CER cells was investigated. Pretreatment of CER cells with concanavalin A inhibited cellular susceptibility to rabies virus infection. The lectin also was found to be inhibitory when applied after the viral binding step. Moreover, the lectin had a direct inhibitory effect on the infectivity of the virion. These lectin-mediated inhibitions could be reversed by .alpha.-D-methyl-mannopyranoside. These complex effects are discussed with regard to the mechanism of rabies virus entry into CER cells.Keywords
This publication has 6 references indexed in Scilit:
- Characterization of saturable binding sites for rabies virusJournal of Virology, 1984
- Mechanism of Rabies Virus Entry into CER CellsJournal of General Virology, 1984
- Epstein-Barr Virus-Lymphoid Cell Interactions III. Effect of Concanavalin A and Saccharides on Epstein-Barr Virus PenetrationJournal of Virology, 1982
- Is the Acetylcholine Receptor a Rabies Virus Receptor?Science, 1982
- Effect of Concanavalin A on Vesicular Stomatitis Virus MaturationJournal of General Virology, 1977
- Isolation and Assay of Rabies Serogroup Viruses in CER CellsIntervirology, 1976