The Reaction of Nitriles with Acyl Chlorides in the Presence of Hydrogen Chloride
- 1 January 1973
- journal article
- review article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1973 (04) , 189-202
- https://doi.org/10.1055/s-1973-22170
Abstract
This review surveys the reactions of nitriles with reactive acyl chlorides in the presence of hydrogen chloride. These reactions provide a new area of synthetic utility of nitriles. 1. Intramolecular Acylations of Nitriles 2. The Reaction of Nitriles with Malonyl Chlorides 3. The Reaction of Nitriles with Carbonyl Chloride 4. The Reaction of Nitriles with N-(α-Chlorobenzylidene)-carbamoyl Chloride 5. Miscellaneous 6. ConclusionKeywords
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