Pathobiology of Acute Myocardial Ischemia
- 15 January 1989
- journal article
- research article
- Published by Taylor & Francis in Hospital Practice
- Vol. 24 (1) , 89-107
- https://doi.org/10.1080/21548331.1989.11703644
Abstract
Reperfusion remains the sole proven means for limiting infarct size, but it may exact a pathologic price. Several observations support the belief that restoration of blood flow may promote the structural disruption of myocytes irreversibly injured by antecedent ischemia. If so, reperfusion would hasten cell death, in effect administering the coup de grace to myocardial tissue.Keywords
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