Is Kidney Perfusion Harmful?

Abstract
To permit routine transplantation of kidneys harvested from cadaver donors, a practical method of short-term in vitro preservation of these organs is obviously necessary. The first method used by most transplant centers was simple cooling of the cadaver kidneys by flushing with chilled physiologic electrolyte solution containing colloid and heparin, and storage at near freezing temperatures until the time of transplantation. However, it was soon evident that this form of in vitro preservation could be used for only a few hours, usually no longer than eight, without producing an unacceptable degree of organ damage. Moreover, to permit maximum use of . . .