Semi-automated radioassay for determination of dihydropyrimidine dehydrogenase (DPD) activity screening cancer patients for DPD deficiency, a condition associated with 5-fluorouracil toxicity

This publication has 14 references indexed in Scilit:

• Potential importance of dihydropyrimidine dehydrogenase (DPD) in cancer chemotherapy
  Pharmacogenetics, 1994
• Severe 5-Fluorouracil Toxicity in a Patient with Decreased Dihydropyrimidine Dehydrogenase Activity
  Cancer Investigation, 1993
• β-Alanine synthase: Purification and allosteric properties
  Archives of Biochemistry and Biophysics, 1992
• Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. A potentially more common pharmacogenetic syndrome
  Cancer, 1991
• Metabolism of pyrimidine analogues and their nucleosides
  Pharmacology & Therapeutics, 1990
• Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity.
  Journal of Clinical Investigation, 1988
• Pyrimidine catabolism: individual characterization of the three sequential enzymes with a new assay
  Biochemistry, 1984
• Degradation of pyrimidines and pyrimidine analogs—Pathways and mutual influences
  Pharmacology & Therapeutics, 1980
• [6] Statistical analysis of enzyme kinetic data
  Published by Elsevier ,1979
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
  Analytical Biochemistry, 1976