Combined Effect of Alcohol and Hypoxia on Flicker Fusion Frequency

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Abstract
On the assumption that moderate lack of O2 might increase the effect of alcohol in man, the deviation in flicker fusion frequency was measured during a combination of alcohol and hypoxia. Alcohol, in doses of 0.5-0.7 g./kg. body wt., when combined with simulated altitude of 10,000 ft. caused in most subjects a greater decrease in flicker fusion frequency than alcohol and hypoxia alone. When the results were related to blood alcohol, a decreased performance was present at concns. of 0.03-0.04% after 2-4 hrs. of hypoxia. There seemed to be a simple addition of effects. The physiol. and practical implications are discussed.