Callophycoic Acids and Callophycols from the Fijian Red Alga Callophycus serratus
- 23 August 2007
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 72 (19) , 7343-7351
- https://doi.org/10.1021/jo071210y
Abstract
Callophycoic acids A−H (1−8) and callophycols A and B (9 and 10) were isolated from extracts of the Fijian red alga Callophycus serratus, and identified by NMR, X-ray, and mass spectral analyses. These natural products represent four novel carbon skeletons, providing the first examples of diterpene−benzoic acids and diterpene−phenols in macroalgae. Compounds 1−10 exhibited antibacterial, antimalarial, and anticancer activity, although they are less bioactive than diterpene-benzoate macrolides previously isolated from this red alga.Keywords
This publication has 21 references indexed in Scilit:
- Hexaprenoid Hydroquinones from the Sponge Haliclona (aka Adocia) sp.Journal of Natural Products, 2006
- Bioactive Diterpenes from the Fruits of Detarium microcarpumJournal of Natural Products, 2006
- Bromophycolides C−I from the Fijian Red Alga Callophycus serratusJournal of Natural Products, 2006
- Novel, Rapid, and Inexpensive Cell-Based Quantification of Antimalarial Drug EfficacyAntimicrobial Agents and Chemotherapy, 2004
- Simple and Inexpensive Fluorescence-Based Technique for High-Throughput Antimalarial Drug ScreeningAntimicrobial Agents and Chemotherapy, 2004
- New Bromoterpenes from the Red Alga Laurencia luzonensisJournal of Natural Products, 2001
- A Novel Extracellular Diterpenoid with Antibacterial Activity from the Cyanobacterium Nostoc communeJournal of Natural Products, 1999
- Iridal-Type Triterpenoids with Ichthyotoxic Activity from Belamcanda chinensisJournal of Natural Products, 1998
- Tolypodiol, an Antiinflammatory Diterpenoid from the Cyanobacterium Tolypothrix nodosaJournal of Natural Products, 1996
- Human Malaria Parasites in Continuous CultureScience, 1976