Isolation and Identification of Minor Components of Commercial Kanamycin
- 1 November 1973
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 4 (5) , 560-563
- https://doi.org/10.1128/aac.4.5.560
Abstract
A fraction enriched in the minor components of the kanamycin complex was prepared from a commercial sample. The enriched fraction was subjected to Amberlite CG-50 and Dowex 1-X2 column chromatography. Two minor components were isolated in addition to the known A, B, and C components. These congeners were identified as paromamine and 6- o -(3-amino-3-deoxy-α- d -glucopyranosyl)- deoxystreptamine. The identification was based on degradation and mass spectral studies.Keywords
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