Abstract
The efficacy of ibuprofen and naproxen-sodium for the treatment of primary dysmenorrhea was evaluated in a double-blind cross-over study in 57 otherwise healthy women. The severity of pain reported by the patients was significantly (P < 0.01) reduced during treatment with both ibuprofen and naproxen-sodium compared to the severity of pain before the firse dose. The mean pain relief during treatment with ibuprofen was significantly (P < 0.05) greater than during treatment with naproxen-sodium in the dosages indicated.