Abstract
Several screening tests are becoming popular based on only short-term survival data and with no evidence that they reduce the rate of late-stage cancers and cancer-specific mortality. An extended follow-up study of the Mayo Lung Project in this issue of the Journal and a recent outcomes analysis of 20 major cancers show no overall mortality reduction despite increases in survival from the date of diagnosis. The authors of both papers say that there is a very real concern about harm that must be addressed, a possibility that often gets short shrift.

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