Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism
- 18 January 2002
- journal article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 315 (3) , 351-371
- https://doi.org/10.1006/jmbi.2001.5211
Abstract
No abstract availableKeywords
This publication has 51 references indexed in Scilit:
- Hydrogen bonds with π-acceptors in proteins: frequencies and role in stabilizing local 3D structures11Edited by R. HuberJournal of Molecular Biology, 2001
- Active-site gorge and buried water molecules in crystal structures of acetylcholinesterase from Torpedo californica 1 1Edited by R. HuberJournal of Molecular Biology, 2000
- Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPsJournal of Molecular Biology, 1999
- Crystal structure of the ternary complex of E. coli purine nucleoside phosphorylase with formycin B, a structural analogue of the substrate inosine, and phosphate (sulphate) at 2.1 Å resolutionJournal of Molecular Biology, 1998
- Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with hypoxanthine at 2.15 Å resolutionJournal of Molecular Biology, 1997
- Reduced surface: An efficient way to compute molecular surfacesBiopolymers, 1996
- Strange Bedfellows: Interactions between Acidic Side-chains in ProteinsJournal of Molecular Biology, 1995
- The CCP4 suite: programs for protein crystallographyActa Crystallographica Section D-Biological Crystallography, 1994
- Formycins A and B and some analogues: selective inhibitors of bacterial (Escherichia coli) purine nucleoside phosphorylaseBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1992
- Properties of two unusual, and fluorescent, substrates of purine-nucleoside phosphorylase: 7-methylguanosine and 7-methylinosineBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1986