Pathogenesis of heart block in a fatal case of dermatomyositis.
- 1 November 1986
- Vol. 56 (5) , 479-482
- https://doi.org/10.1136/hrt.56.5.479
Abstract
Approximately 70% of patients with dermatomyositis have evidence of cardiac damage; in one third of cases this affects principally or solely the conduction tissue. In infants similar histological lesions have been associated with a maternal autoantibody, anti-Ro, that crosses the placenta and produces congenital heart block. Anti-Ro antibody was detected in a fatal case of dermatomyositis with lesions of the conduction system.Keywords
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