Contact Urticaria From Cobalt Chloride

Abstract
• Cobalt chloride should be added to the ever growing list of contact urticants. This chemical is frequently used as a color indicator in provocative sweat testing. In this case, contact urticaria was probably nonimmunologic in origin. Since diphenhydramine and 48-80 (polymonine) block this reaction to cobalt chloride, vasoactive amines are at least partially responsible for the urticaria. (Arch Dermatol111:1610-1611, 1975)

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