Proteome chips for whole-organism assays
- 24 May 2006
- journal article
- review article
- Published by Springer Nature in Nature Reviews Molecular Cell Biology
- Vol. 7 (8) , 617-622
- https://doi.org/10.1038/nrm1941
Abstract
Over the past 5 years, protein-chip technology has emerged as a useful tool for the study of many kinds of protein interactions and biochemical activities. The construction of Saccharomyces cerevisiae whole-proteome arrays has enabled further studies of such interactions in a proteome-wide context. Here, we explore some of the recent advances that have been made at the '-omic' level using protein microarrays.Keywords
This publication has 50 references indexed in Scilit:
- High Throughput Identification of Potential Arabidopsis Mitogen-activated Protein Kinases SubstratesMolecular & Cellular Proteomics, 2005
- Human ORFeome Version 1.1: A Platform for Reverse ProteomicsGenome Research, 2004
- Functional protein microarrays: ripe for discoveryCurrent Opinion in Chemical Biology, 2004
- C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expressionNature Genetics, 2003
- Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiaeGenes & Development, 2002
- Transcriptional Regulatory Networks in Saccharomyces cerevisiaeScience, 2002
- Functional organization of the yeast proteome by systematic analysis of protein complexesNature, 2002
- A comprehensive two-hybrid analysis to explore the yeast protein interactomeProceedings of the National Academy of Sciences, 2001
- Life with 6000 GenesScience, 1996
- Multi-analyte immunoassayJournal of Pharmaceutical and Biomedical Analysis, 1989