Chromosome abnormalities in breast fibroadenomas
- 1 May 1991
- journal article
- research article
- Published by Wiley in Genes, Chromosomes and Cancer
- Vol. 3 (3) , 202-204
- https://doi.org/10.1002/gcc.2870030305
Abstract
A cytogenetic study on 25 breast fibroadenomas from 17 women is reported. Seven tumors in five patients showed clonal structural chromosome changes. In three patients the breaks involved chromosome 12, occurring in two tumors in band 12p 12 and in band 12q 15 in all three tumors of one patient. The finding of an identical aberration, t(11;12)(q21;q15), in three adenomas from the same patient strongly suggests a clonal origin of multiple fibroadenomas of the breast.Keywords
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