Trazodone by Intravenous Infusion in Depressions Secondary to Organic Disease
- 1 July 1977
- journal article
- research article
- Published by S. Karger AG in International Pharmacopsychiatry
- Vol. 12 (2) , 72-79
- https://doi.org/10.1159/000468290
Abstract
16 patients with organic depression were treated with low doses of trazodone (100 mg/day) by i.v. infusion. This drug was shown to have a marked antidepressant and anxiolytic action and did not produce any significant side-effects. The authors suggest that on the basis of the diminished 24-hour urinary excretion of 5-HIAA, trazodone seems to have an antiserotonin action at low doses.Keywords
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