Acute phosphine poisoning aboard a grain freighter. Epidemiologic, clinical, and pathological findings

Publisher Website
Google Scholar
Abstract
Two children and 29 of 31 crew members aboard a grain freighter became acutely ill after inhaling the toxic fumigant [used against insects and rodents] phosphine; 1 child died. Predominant symptoms were headache, fatigue, nausea, vomiting, cough and shortness of breath. Abnormal physical findings included jaudice, paresthesias, ataxia, intention tremor and diplopia. Focal myocardial infiltration with necrosis, pulmonary edema and widespread small-vessel injury were found at postmortem examination of the dead child. The surviving child showed ECG and echocardiographic evidence of myocardial injury and transient elevation of the MB fraction of serum creatinine phosphokinase. Illness was significantly associated with living or working amidships or on the forward deck areas of the vessel. Phosphine gas excaped from the holds through a cable housing located near the midships ventilation intake and around hatch covers on the forward deck. The outbreak illustrates the hazards associated with shipboard fumigation.

This publication has 1 reference indexed in Scilit: