Normal Plasma Gonadotropin Response to Gonadotropin-Releasing Hormone after Diethylstilbestrol Priming in Transsexual Women
- 1 July 1983
- journal article
- other
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 57 (1) , 197-199
- https://doi.org/10.1210/jcem-57-1-197
Abstract
Plasma LH and FSH responses to GnRH (100 μg, iv) were measured in four female transsexuals with normal ovulatory menstrual cycles before and after the administration of 2.0 mg diethylstilbestrol (DES) daily for 7 days. One normal ovulatory woman was also studied in the early follicular phase of the menstrual cycle. No difference was found in the augmented response of the four female transsexuals to GnRH after DES priming from that of the normal adult female. The augmented response to GnRH found in the female transsexuals after DES treatment provides evidence that hypothalamic-pituitary feedback control is normal in the female transsexuals studied.Keywords
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