Abstract
In investigations on the effect of different chemical substances on isolated mouse liver cells, the behavior of the cells under the action of direct current was studied also under the phase contrast microscope. Four different events were observed: migration of whol''e cells and isolated cell nuclei to the anode; migration of the contents of the nucleus likewise to the anode side; shrinking and swelling processes which evidently depend upon a change in the pH of the medium surrounding the cell; changes in the cell membrane and in the so-called potocytosis vesicles which are not to be referred to a change in the pH of the medium surrounding the cells. The preceding observations are compared with the results of other authors and the mode of action of the electric current with respect to morphological phenomena is discussed.