On the chemical binding of 6β-bromopenicillanic acid to β-lactamase I
- 1 January 1979
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 21,p. 962-963
- https://doi.org/10.1039/c39790000962
Abstract
6β-Bromopenicillanic acid (1) binds to serine-44 of the β-lactamase I from B. cereus as a dihydrothiazine derivative, which undergoes further chemical changes during cleavage of the enzyme.Keywords
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