LOCALIZED NODULAR MYOSITIS - CLINICAL AND PATHOLOGICAL VARIANT OF POLYMYOSITIS

  • 1 January 1977
    • journal article
    • research article
    • Vol. 46  (184) , 531-546
Abstract
Three cases of a painful, inflammatory, nodular myopathy in young and middle-aged adult males are described. In 2 cases the nodular process gradually evolved into a diffuse proximal myopathy accompanied by dysphagia and manifesting the so-called facioscapulohumeral syndrome. The electromyogram (EMG) in all 3 cases was myopathic in type, and in 2 cases abnormalities cosistent with an inflammatory muscle disorder are seen. Muscle biopsy reveals a consistent pattern of intense, predominantly interstitial, pleomorphic infiltration of muscle with scattered foci of muscle fiber destruction and regeneration, which resemble muscle infarcts. This syndrome, while readily recognizable from the clinical and pathological standpoints, is not a nosological entity, but rather an unusual presentation of polymyositis.

This publication has 0 references indexed in Scilit: