2-Cyanoethyl H-Phosphonate. A Reagent for the Mild Preparation of Nucleoside H-Phosphonate Monoesters

1 May 1995

journal article
Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids

Vol. 14 (3) , 715-716
https://doi.org/10.1080/15257779508012456

Abstract

2-Cyanoethyl H-phosphonate was condensed with protected nucleoside derivatives and the cyanoethyl group subsequently removed by anhydrous base to give the corresponding nucleoside H-phosphonate in good yield.

Keywords

REAGENT
PHOSPHONATE
GOOD
MONOESTERS
CONDENSED
ANHYDROUS
GIVE
CORRESPONDING
REMOVED
CYANOETHYL

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