ANTIBODIES IN RHESUS-MONKEYS AFTER EXPERIMENTAL-INFECTION WITH AFRICAN LUNG-WORMS (PARAGONIMUS-UTEROBILATERALIS AND PARAGONIMUS-AFRICANUS)
- 1 January 1977
- journal article
- research article
- Vol. 28 (4) , 539-544
Abstract
Serological studies on experimentally infected Macaca mulatta with P. uterobilateralis and P. africanus supported by parasitological findings and chest X-ray experiments from other authors are reported. Chronologically serological changes were 1st noticed in the animals followed by X-ray changes of the lungs. Somewhat later the monkeys started excretion of worm-eggs. Egg production did not take place in all monkeys and showed individual variation. The passive hemagglutination and complement fixation test were suitable serological methods to indicate a Paragonimus infection in monkeys. In older infections the complement fixation test was not a suitable as the passive hemagglutination since the complement fixing antibodies lost most of their activity within 6-8 mo. Antigenic relationship between the 2 African Paragonismus spp. could be demonstrated by cross-reactions with passive hemagglutination, complement fixation and double gel diffusion test. Disc-electrophoresis proved that there were 2 taxonomically different Paragonimus-spp. in Africa.This publication has 4 references indexed in Scilit:
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