An attempt to isolate and identify allergens in lanolin

Abstract
One sensitizer, a sterol, has previously been reported to be present in lanolin. In this study, a related substance, a sterol with 424 [dalton] MW was isolated. A few sensitive subjects did not react to this substance. Lanolin probably contains several sensitizers. Sensitization to lanolin in guinea pigs seems previously to have failed. In this study, a methanol extract of a lanolin preparation containing large amounts of sterols sensitized guinea pigs.

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