CA 15.3 - EARLY RESULTS OF A NEW BREAST-CANCER MARKER

  • 1 July 1986
    • journal article
    • research article
    • Vol. 6  (4) , 683-684
Abstract
A new antigen associated with breast cancer, CA 15.3, was determined in the serum of 690 breast cancer patients and controls. After establishing a maximum normal level of 40 U/ml in 140 healthy subjects and 350 patients with benign diseases, CA 15.3 was investigated in 190 breast cancer patients: CA 15.3 serum levels were statistically different in patients with no evidence of disease (20.6 .+-. 11.2 U/ml), metastic patients in response (33.5 .+-. 24.0 \ml) and metastatic patients not responding to therapy (stable disease, 98.9 .+-. 50.4; progression, > 200). CA 15.3 serum levels seem to correlate with the extent of metastatic breast cancer. Further studies are needed to establish the role of this marker in the management of breast cancer patients.