Neonatal alloimmune thrombocytopenic purpura associated with sensitization against the platelet‐specific antigen Yuka

Abstract
We report a Japanese newborn who developed alloimmune thrombocytopenia by the antibodies to the newly discovered platelet antigen Yuka. The infant recovered uneventfully in 10 days without specific treatment. Antiplatelet ailoantibodies in the patient were IgG class detected by mixed passive hemagglutination (MPHA). Family study showed that Yuka antigen was inherited as an autosomal dominant trait. Cases with Yuka‐associated alloimmune thrombocytopenia are reviewed.