EFFECT OF HEPARIN ON ACTIVATED PARTIAL THROMBOPLASTIN TIME

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  • 1 January 1978
    • journal article
    • research article
    • Vol. 70  (3) , 556-559
Abstract
Data from the 1976 and 1977 CAP [College of American Pathologists] surveys were analyzed for response of the activated partial thromboplastin time (APTT) to heparin. Different sources and concentrations of heparin were used. The precision of the APTT was apparently more dependent on instrumentation than on partial thromboplastin. This was true for all 4 of the heparinized specimens evaluated. A single exception was found with the old Dade reagent activated cephaloplastin. The mean difference in the activated partial thromboplastin times obtained with differing concentrations of heparin was entirely dependent on the partial thromboplastin reagent used. No significant difference in the results was found when equal concentrations of bovine lung and porcine intestinal mucosal heparin were compared.

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