IgA and IgM Antibodies against Mycobacterium leprae in Cord Sera and in Patients with Leprosy: An Indicator of Intrauterine Infection in Leprosy
- 1 October 1981
- journal article
- research article
- Published by Wiley in Scandinavian Journal of Immunology
- Vol. 14 (4) , 343-352
- https://doi.org/10.1111/j.1365-3083.1981.tb00574.x
Abstract
A solid-phase radioimmunoassay was developed for demonstration and quantification of IgA and IgM anti-M. leprae antibodies. IgA and IgM anti-M. leprae antibodies were demonstrated in a lepromatous serum pool, in various amounts in individual patients with lepromatous leprosy, and in lower concentration in tuberculoid leprosy and non-leprosy controls. IgA and IgM anti-M. leprae antibodies were demonstrated in cord sera from babies of mothers with leprosy. The reliability of fetal IgA and IgM antibody synthesis as an indicator of intrauterine infection in leprosy is discussed.This publication has 26 references indexed in Scilit:
- Antigenic Analysis of Mycobacterium lepraeScandinavian Journal of Immunology, 1979
- Antibodies against BCG antigen 60 in mycobacterial infection.BMJ, 1977
- Rheumatoid factor: Its nature, specificity, and production in rheumatoid arthritisClinical Immunology and Immunopathology, 1976
- Recognition of Two Distinct Groups of Human IgM and IgA Based on Different Binding to StaphylococciScandinavian Journal of Immunology, 1974
- The IgM FTA Test for Syphilis in the NewbornAustralian and New Zealand Journal of Obstetrics and Gynaecology, 1972
- The Continuous Bacteremia of Lepromatous LeprosyNew England Journal of Medicine, 1972
- Unusual primary tuberculosisTubercle, 1965
- Congenital RubellaAmerican Journal of Diseases of Children, 1965
- Studies on Antibody in Congenital Rubella InfectionsAmerican Journal of Diseases of Children, 1965
- Clinical Aspects of Congenital TuberculosisArchives of Disease in Childhood, 1956