Inhibition of Specific Effector T Cell-Target Cell Conjugates by Target Cell Plasma Membranes

Open Access

1 March 1978

journal article
research article
Published by Oxford University Press (OUP) in The Journal of Immunology

Vol. 120 (3) , 774-776
https://doi.org/10.4049/jimmunol.120.3.774

Abstract

Conjugate formation between effector T cells raised in vivo in a BALB/c host and fluorescein diacetate-labeled allogeneic EL4 tumor target cells was observed and scored by using a fluorescence microscope. This conjugate formation was found to be specifically inhibited by plasma membrane vesicles isolated from the EL4 cells.