METHOD FOR SEROLOGICAL DIFFERENTIATION OF CLOSELY RELATED POXVIRUSES

1 January 1976

journal article
research article

Vol. 20 (3) , 250-+

Abstract

A two-step gel precipitation reaction with antiserum to vaccinia virus, based on sequential addition of 2 test viruses was elaborated for differentiation of closely related orthopoxviruses. The appearance of an additional precipitation line indicated differences in the antigenic structure of the viruses compared. Differences in the antigenic structure of vaccinia, variola and monkey poxviruses and the antigenic identity with cow poxvirus of poxviruses isolated from carnivora, elephants and okapi were established.

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