Invasive Aspergillosis

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Abstract
There is an increasing frequency of mycotic infections in patients with leukemia and other hematologic neoplasia.1 2 3 Aspergillosis is second only to candidiasis in frequency of opportunistic fungal disease among such patients.2 3 4 5 6 Invasive aspergillosis is difficult to diagnose and is often lethal in the immunosuppressed host.5 , 7 Blood cultures3 , 8 and serologic tests9 are usually negative with systemic disease. Skin lesions are infrequently reported in large series of patients with invasive aspergillosis3 , 7 , 10 , 11; however, we have observed cutaneous involvement in four patients during the past two years. The purpose of this paper is to describe the characteristic morphology of the skin lesions in . . .

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