Efficient One-Pot Synthesis of Cyclopenta[b]thiophen-1-ones and 1,3-Di(2-thiophenyl)propan-1-ones from Thiophenes

Abstract
The reaction of N,N-dimethylacrylamide/triflic anhydride complex with substituted thiophenes led to the corresponding cyclopenta[b]thiophen-1-ones and 1,3-di(2-thiophenyl)propan-1-ones. The application of 2-bromo-N,N-dimethylacrylamide in this reaction allows 2-bromo-substituted five- or seven-membered thiophene-fused cyclic ketones to be obtained.

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