Immunoglobulin Classes of Serum Neutralizing Antibody Formed in Response to Infection with Human A2 Influenza Virus

Publisher Website
Google Scholar
Abstract
In volunteers the sequential appearance of the immunoglobulin [Ig] classes of neutralizing antibody formed as a result of infection with A2/Bethesda/10/63 influenza was studied. The antibody appeared in the IgG class and no significant antibody in the IgM or IgA classes was found. It was particularly notable that no IgM antibody could be detected 7 days after inoculation. The pattern of antibody against A2/Japan/305/57 was nearly identical to that formed against the inoculum strain. Antibody rises were also noted against A/PR8 and A1/FM1 influenza viruses.