Radiation, Chromosomes and Viruses in the Etiology of Leukemia
- 2 July 1964
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 271 (1) , 30-36
- https://doi.org/10.1056/nejm196407022710106
Abstract
IN the last decade epidemiologic research has contributed evidence implicating ionizing radiation and chromosomal aberrations in the genesis of leukemia. By comparison, the epidemiologic evidence for the viral etiology of human leukemia is scanty despite the anticipation generated by continuing successes in identifying leukemogenic viruses in mice.As is true of other research approaches, epidemiology may describe a disease, explore it empirically or test specific ideas about it. The patterns of leukemia mortality that have been ascertained by descriptive epidemiology, though they do not per se suggest the etiology, do provide considerable intelligence against which suspected principal causes of the . . .Keywords
This publication has 51 references indexed in Scilit:
- Tumour-viruses and Virus-tumoursBMJ, 1964
- Radiation-Induced Mouse Leukemia: Consistent Occurrence of an Extra and a Marker ChromosomeScience, 1964
- EFFECTS OF DIAGNOSTIC IRRADIATIONThe Lancet, 1963
- Klinefelter's syndrome, Down's syndrome (Mongolism), and twinning in the same sibship: Chromosomal studies in 2 familiesThe Journal of Pediatrics, 1963
- An Abnormal Chromosome in Chronic Lymphocytic LeukaemiaBMJ, 1962
- TWO CASES OF LEUKÆMIA AND A CASE OF SEX-CHROMOSOME ABNORMALITY IN THE SAME SIBSHIPThe Lancet, 1961
- A FAMILY WITH AN XXXXY MALE, A LEUKÆMIC MALE, AND TWO 21-TRISOMIC MONGOLOID FEMALESThe Lancet, 1961
- LEUKqMIA ASSOCIATED WITH MONGOLISMThe Lancet, 1961
- Acute Myeloid Leukaemia in AdolescentsBMJ, 1961
- Incidence of Leukaemia in Singapore, and Rarity of Chronic Lymphocytic Leukaemia in ChineseBMJ, 1960