Exercise‐induced protection against myocardial apoptosis and necrosis: MnSOD, calcium‐handling proteins, and calpain
Open Access
- 19 March 2008
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 22 (8) , 2862-2871
- https://doi.org/10.1096/fj.07-102541
Abstract
Exercise provides protection against myocardial ischemia‐reperfusion (IR) injury. Understanding the mechanisms of this protection may lead to new interventions for the prevention and/or treatment of ...Keywords
Funding Information
- National Institutes of Health (R01 067855–01)
- National Heart, Lung, and Blood Institute
- American Heart Association (0415135B)
This publication has 55 references indexed in Scilit:
- Cardiomyocyte Degeneration With Calpain Deficiency Reveals a Critical Role in Protein HomeostasisCirculation Research, 2007
- TNF-α-mediated cardiomyocyte apoptosis involves caspase-12 and calpainBiochemical and Biophysical Research Communications, 2006
- Ischemia-reperfusion-induced calpain activation and SERCA2a degradation are attenuated by exercise training and calpain inhibitionAmerican Journal of Physiology-Heart and Circulatory Physiology, 2006
- Calpain inhibitor-1 protects the rat heart from ischemia-reperfusion injury: analysis by mechanical work and energeticsAmerican Journal of Physiology-Heart and Circulatory Physiology, 2005
- Ischemia/reperfusion injury at the intersection with cell deathJournal of Molecular and Cellular Cardiology, 2005
- MnSOD antisense treatment and exercise-induced protection against arrhythmiasFree Radical Biology & Medicine, 2004
- Elevated MnSOD is not required for exercise-induced cardioprotection against myocardial stunningAmerican Journal of Physiology-Heart and Circulatory Physiology, 2004
- Functional Interactions of Cytoplasmic Domains of the Skeletal Muscle Ca2+ Release ChannelTrends in Cardiovascular Medicine, 1998
- Effects of oxygen free radicals on isolated cardiac myocytes from guinea-pig ventricle: Electrophysiological studiesJournal of Molecular and Cellular Cardiology, 1992
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976