Site-directed mutagenesis of mouse dihydrofolate reductase. Mutants with increased resistance to methotrexate and trimethoprim.

This publication has 49 references indexed in Scilit:

• The structure of mouse L1210 dihydrofolate reductase‐drug complexes and the construction of a model of human enzyme
  FEBS Letters, 1987
• Mechanism of inhibition of dihydrofolate reductases from bacterial and vertebrate sources by various classes of folate analogues
  Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1986
• Site‐specific mutagenesis of dihydrofolate reductase from Escherichia coli
  Journal of Cellular Biochemistry, 1985
• The pH-dependence of the binding of dihydrofolate and substrate analogues to dihydrofolate reductase from Escherichia coli
  Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1983
• Purification and characterization of dihydrofolate reductase from methotrexate-resistant human lymphoblastoid cells
  Biochemistry, 1983
• Kinetic mechanism of the reaction catalyzed by dihydrofolate reductase from Escherichia coli
  Biochemistry, 1982
• Structure and genomic organization of the mouse dihydrofolate reductase gene
  Cell, 1980
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
  Analytical Biochemistry, 1976
• Bovine liver dihydrofolate reductase. Purification and properties of the enzyme
  Biochemistry, 1975
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
  Nature, 1970