Differential Effect of Amphetamine Optical Isomers on Bender Gestalt Performance of the Minimally Brain Dysfunctioned

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Abstract
As part of a double-blind Latin-square crossover comparison of placebo, dextroamphetamine and levoamphetamine in 31 hyperkinetic minimally brain dysfunctioned children, Bender Gestalt tests were administered. On mean Koppitz error scores, dextroamphetamine showed significant benefit over predrug, placebo, and levoamphetamine. Predrug, placebo, and levoamphetamine Koppitz scores were not significantly different from one another, though all three were significantly worse than dextroamphetamine. Dosages of the two isomers were not significantly different, and behavioral effects were comparable.