Antidotal Properties of Crude Penicillium notatum Filtrate
- 1 June 1947
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 65 (2) , 172-175
- https://doi.org/10.3181/00379727-65-15899
Abstract
The in vitro results on the antidotal factor reported by Ramon, et al., are essentially corroborated. This antidotal agent is dialyz-able. The antidotal activity is inactivated in the presence of blood. No in vivo therapeutic activity against tetanus toxin or pertussis endotoxin could be demonstrated. Results indicate that this agent not only detoxifies toxin but also destroys antigenicity.Keywords
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