Mianserin in the Prophylactic Treatment of Bipolar Affective Illness
- 1 July 1977
- journal article
- research article
- Published by S. Karger AG in International Pharmacopsychiatry
- Vol. 12 (2) , 95-99
- https://doi.org/10.1159/000468293
Abstract
Mianserin in a dosage of 20 mg 3 times daily was given to 13 patients with bipolar affective illness, previously maintained on Li. Patients (2) left the trial in a few days because of drowsiness and 1 because of insomnia; within the 3-mo. trial period 6 became manic. Mianserin may be capable of precipitating mania in susceptible subjects with bipolar affective illness. This may be a general antidepressant property since it has been described with other antidepressants.This publication has 1 reference indexed in Scilit: