Turnover in periodontal connective tissues: dynamic homeostasis of cells, collagen and ground substances

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Abstract
The connective tissues of the periodontium are composed of two soft tissues and two hard tissues--each of which has unique features. This review considers the constituents of normal, healthy periodontal connective tissues together with an appraisal of the changes in the connective tissue matrices of the periodontium which occur during the development of periodontitis. Recent developments in this field have paved the way for new and exciting vistas in periodontal diagnosis and regeneration which, ultimately, are two important goals in periodontal therapy.