A simple whole-body counter for measuring radionuclides in large dogs

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Abstract
Studies of absorption and retention of radionuclides in animals are commonly undertaken to suggest possible mechanisms for metabolic processes occurring in man, and to observe the effects of various agencies upon them. The retention of 47Ca by greyhounds was measured as part of a wider study of Ca metabolism in human metabolic bone disease, and, in dogs of this size, variation in counting efficiency due to changing distribution of radioactivity presents a considerably greater problem. Up to 50 .mu.Ci 47Ca had to be administered to permit long term measurements of plasma radioactivity, so it was possible to overcome this problem by using a sensitive large area detector 60 cm from the dog, which was placed in a specially constructed counting chamber. Although the counter described incorporates a plastic scintillator detector previously used in a human whole-body counter, the present application is typical of those for which a liquid scintillator detector module is recommended.

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